CBD and Nausea: A Natural Remedy for Nausea and Vomiting

Introduction

Nausea and vomiting are common symptoms linked to multiple causes: gastrointestinal disorders, chemotherapy, pregnancy, stress, migraines, or medication side effects. Although often temporary, they can significantly impact daily well-being.

In recent years, the use of CBD (cannabidiol) as a natural remedy for nausea and vomiting has attracted growing interest, both among researchers and those seeking alternatives to traditional medications, which often have side effects.

In this article, we'll clearly and easily analyze what science says about the link between CBD and nausea , its mechanisms of action, and how to use it safely and effectively.

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What is CBD?

CBD , or cannabidiol, is one of the main non-psychoactive compounds in Cannabis sativa . Unlike THC, it does not alter perception or consciousness, but interacts with the body's endocannabinoid system (ECS) , a complex regulatory system that involves fundamental functions such as:

• Humor

• Perception of pain

• Appetite

• Digestion

• Immune response

This interaction makes it particularly interesting in the symptomatic treatment of nausea and vomiting .

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CBD for nausea and vomiting: what does science say?

🧠 It acts on serotonin receptors

CBD can modulate serotonin 5-HT1A receptors , a neurotransmitter involved in regulating nausea. This action partly explains why CBD can reduce nausea and prevent vomiting , especially when related to neurological disorders or medication.

📚 A study published in the British Journal of Pharmacology showed that CBD exerts antiemetic effects in animal models, acting directly on the brain and central nervous system.
🔗 Source

💊 Useful against nausea from chemotherapy

Chemotherapy-induced nausea and vomiting (CINV) is among the most debilitating symptoms for cancer patients. Clinical studies suggest that CBD, even in combination with THC, can reduce the intensity of these symptoms and improve treatment adherence.

🔬 A review published in Frontiers in Pharmacology has highlighted the potential of CBD in the treatment of refractory nausea in cancer patients.
🔗 Source

🤰 Safe during pregnancy? Caution!

Many pregnant women experience morning sickness. However, CBD use during pregnancy is not yet officially recommended due to a lack of sufficient human clinical studies. It's essential to discuss this with your doctor before use.

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How do you take CBD for nausea?

The method of administration significantly affects the speed and effectiveness of the anti-nausea effect.

👉 Start with low doses (e.g., 5–10 mg) and increase only if necessary. Always consult a doctor, especially if you have a pre-existing medical condition or are taking concomitant medications.

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Side effects and precautions

CBD is generally well tolerated , but can cause:

• Drowsiness

• Dry mouth

• Diarrhea (at high doses)

• Drug interactions (e.g. anticoagulants, anxiolytics)

⚠️ Do not use CBD during pregnancy or breastfeeding without consulting your gynecologist.
⚠️ Make sure the product is certified, lab-tested , and THC-free (or less than 0.2% if required by law).

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Conclusions

CBD is proving to be a promising ally in managing nausea and vomiting , both acute and chronic. Thanks to its interaction with serotonin receptors and its anti-inflammatory effect, it may represent a valid natural alternative to traditional antiemetic drugs.

However, it is important to remember that every body reacts differently, and that the effectiveness of CBD depends on many factors: dosage, type of symptom, form of administration, and individual conditions.

✅ For safe and effective use, rely on quality products and seek advice from a healthcare professional.

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📚 Scientific sources

1. Parker LA et al. (2011). Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behavior via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus.
   🔗 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165951/

2. Rock EM et al. (2016). Cannabinoids and the Regulation of Nausea and Vomiting.
   🔗 https://www.frontiersin.org/articles/10.3389/fphar.2016.00221/full

3. Baron EP. (2015). Comprehensive Review of Medicinal Marijuana, Cannabinoids, and Therapeutic Implications in Medicine and Headache.
   🔗 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/